Endometriosis and gut disorders have a genetic link

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The disease can cause cysts, severe cramping, heavy periods and infertility. Photo: Pexels

 

(Emily Cooke/ Live Science) — A new study has revealed specific gene variants associated with a higher risk of both endometriosis and several digestive disorders, such as IBS and GERD.

Scientists have identified a genetic link between endometriosis and several digestive disorders, including irritable bowel syndrome (IBS).

Endometriosis, which affects roughly 1 in 10 reproductive-age women, is caused by the growth of tissue that resembles the lining of the uterus in other parts of the body, such as the fallopian tubes, ovaries, bladder or bowel. The disease can cause cysts, severe cramping, heavy periods and infertility. It is also commonly associated with gastrointestinal (GI) issues, although the relationship between endometriosis and common GI disorders is not well understood.

In a new study, published Thursday (Oct. 26) in the journal Cell Reports Medicine, scientists found observational evidence from a dataset of almost 190,000 women that suggests those with endometriosis are at a higher risk of having certain GI conditions, including diseases of the gut. (…)

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