A surgically implanted brain stimulation device could help treat severe depression

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The trial used a technique called deep brain stimulation, where electrodes implanted within the brain deliver electrical impulses in an attempt to change or regulate abnormal brain activity.

 

(Nicole Wetsman/ The Verge) — Sarah had no options left. Over five years, she’d tried every possible treatment for her severe depression, and nothing had helped. “My daily life had become so restricted and impoverished by depression that I felt tortured by each day,” the 36-year-old said.

But after undergoing an experimental procedure that implanted a device into her brain, she felt her depression lift for the first time in years. “It was like my lens on the world changed,” Sarah, who is remaining anonymous because of the stigma around depression, said during a press briefing.

Sarah was the patient in a proof-of-concept trial of a new approach to treating severe, treatment-resistant depression, published today in the journal Nature Medicine. The findings open up another possible strategy for helping people with the disorder. The study only involved Sarah, and it’s still not clear how well it might work in other people. The lessons from the trial, though, helped the researchers understand more about the nature of depression and could apply to other efforts to treat the disease. (…)

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